abstract：CONCLUSIONS:The present study revealed that miR-21 promotes the proliferation and invasion of cholesteatoma keratinocytes. These results provide a partial explanation for the more aggressive clinical behavior observed in cholesteatoma. OBJECTIVE:This study aims to investigate the post-transcriptional regulatory effect...

journal_title：Acta oto-laryngologica

authors： Chen X,Li X,Qin Z

更新日期：2016-12-01 00:00:00

abstract：CONCLUSION:Diazepam can reduce the excitability of lateral amygdala and eventually suppress the excitability of the auditory cortex in rats following salicylate treatment, indicating the regulating effect of lateral amygdala to the auditory cortex in the tinnitus procedure. OBJECTIVE:To study the spontaneous firing ra...

journal_title：Acta oto-laryngologica

authors： Song Y,Liu J,Ma F,Mao L

更新日期：2016-12-01 00:00:00

abstract：CONCLUSIONS:There was a difference in average score of the sensory organization test (SOT) of the case group (elderly instability) compared to the control group (healthy subjects). Cases had worse scores on the limits of stability (LOS) than controls, but were only able to confirm statistically significant differences ...

journal_title：Acta oto-laryngologica

authors： Faraldo-García A,Santos-Pérez S,Rossi-Izquierdo M,Lirola-Delgado A,Vaamonde-Sánchez-Andrade I,Del-Río-Valeiras M,Soto-Varela A

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:The authors would like to confirm a fluid pathway from the scala tympani to the organ of Corti, and to observe its morphological changes. METHODS:A staining solution for succinic dehydrogenase was perfused with phenazine methosulfate in the scala tympani of living guinea pigs (n = 5) under deep anesthesia. ...

journal_title：Acta oto-laryngologica

authors： Nomura Y,Kimura Y,Kobayashi H

更新日期：2016-11-01 00:00:00

abstract：CONCLUSION:In the mouse, when a tympanic perforation is present, gadoteridol does not seem to cause ototoxicity. Gadodiamide may cause mild ototoxicity other than toxicity to the outer hair cells of the cochlea. OBJECTIVES:Endolymphatic hydrops have been visualized through intra-tympanic injection of gadolinium-based ...

journal_title：Acta oto-laryngologica

authors： Nonoyama H,Tanigawa T,Shibata R,Tanaka H,Katahira N,Horibe Y,Takemura K,Murotani K,Ozeki N,Ueda H

更新日期：2016-11-01 00:00:00

abstract：CONCLUSION:It is thought that oxidative stress may be the major cause of the increase in the oxide thiol form in the study group. The relationship between oxidative stress status and dynamic thiol/disulphide in nasal polyposis now needs to be investigated. OBJECTIVES:The purpose of this study was to evaluate the relat...

journal_title：Acta oto-laryngologica

authors： Şimşek E,Erel O,Bicer CK,Çarlıoğlu A

更新日期：2016-11-01 00:00:00

abstract：CONCLUSION:The sensitive sonotubometry and MATLAB provide a new tool to study the eustachian tube (ET) function and contribute more to reliable data and precise analysis. The levator veli palatini muscle (mLVP) and the salpingopharyngeus muscle (mSP) may, respectively, be the most important and least important muscle f...

journal_title：Acta oto-laryngologica

authors： Lin C,Li Y,Lin X,Zhang S,Tang A,Nong D

更新日期：2016-11-01 00:00:00

abstract：CONCLUSION:Nitric oxide synthase (NOS) II induction is a protective mechanism against age-related degeneration of the cochlea. OBJECTIVES:An induction of NOS II has been described in different inner ear pathologies. The objective was to examine the role of NOS II in age-related degeneration of the cochlea. METHODS:Th...

journal_title：Acta oto-laryngologica

authors： Labbé D,Bloch W,Schick B,Michel O

更新日期：2016-10-01 00:00:00

abstract：CONCLUSION:This study shows that, in cochlear implantation (CI) surgery, pre-operative caloric test results are not correlated with post-operative outcomes of dizziness or speech perception. OBJECTIVES:To determine the role of pre-operative caloric tests in CI. METHODS:The records of 95 patients who underwent unilate...

journal_title：Acta oto-laryngologica

authors： Yang CJ,Lee JY,Ahn JH,Lee KS

更新日期：2016-09-01 00:00:00

abstract：CONCLUSION:The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression. OBJECTIVE:To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the sa...

journal_title：Acta oto-laryngologica

authors： Sapmaz E,Uysal M,Tumer MK,Sapmaz HI,Somuk BT,Arici A,Tas U

更新日期：2016-09-01 00:00:00

abstract：CONCLUSION:Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid h...

journal_title：Acta oto-laryngologica

authors： Alex-Okoro J,Orji FT,Umedum NG,Akpeh JO

更新日期：2016-09-01 00:00:00

abstract：:Conclusion Eustachian tube (ET) dysfunction, which plays a role in the pathogenesis chronic suppurative otitis media (CSOM), does not seem to be due to differences in paratubal structures. Objective The aim of this study was to compare the magnetic resonance imaging (MRI) findings of the paratubal structures of the ET...

journal_title：Acta oto-laryngologica

authors： Terzi S,Beyazal Çeliker F,Özgür A,Çeliker M,Beyazal M,Demirci M,Dursun E

更新日期：2016-07-01 00:00:00

abstract：:Conclusions Endoscopic surgery is safe and effective for children with congenital basal meningoencephaloceles (CBMs); it provides an acceptable operative outcome with a short recovery time and fewer complications and may be considered as a primary approach. Objectives To explore the safety and effectiveness of using t...

journal_title：Acta oto-laryngologica

authors： Wu X,Zhang J,Zhang H,Xie Z,Fan R,Liu Y,Wu B,Sun H,Jiang W

更新日期：2016-06-01 00:00:00

abstract：CONCLUSION:MCT is a useful tool to pre-operatively determine whether internal nasal valve (INV) narrowing affects a nasal obstruction. Functional rhinoplasty seemed to produce better results than septoplasty in Asian patients with a nasal obstruction, due to INV narrowing. OBJECTIVE:This study compared pre-operative m...

journal_title：Acta oto-laryngologica

authors： Kwun C,Yang CW,Kim SW,Lee KH

更新日期：2016-01-01 00:00:00

abstract：CONCLUSION:This study described objective and subjective evaluations of the Nurotron® Venus™ Cochlear Implant System and indicated that this system produced a satisfactory performance. OBJECTIVE:To observe the performance of the Nurotron® Venus™ cochlear implant (CI) system via electrophysiological and psychophysical ...

journal_title：Acta oto-laryngologica

authors： Gao N,Xu XD,Chi FL,Zeng FG,Fu QJ,Jia XH,Yin YB,Ping LC,Kang HY,Feng HH,Wu YZ,Jiang Y

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between hearing loss and vestibular dysfunction in patients with sudden sensorineural hearing loss (SSHL). METHODS:Clinical data including the symptom of vertigo of 149 SSHL patients were investigated retrospectively. Pure tone audiometry, ocular vestibular-evoked myogenic pot...

journal_title：Acta oto-laryngologica

authors： Niu X,Zhang Y,Zhang Q,Xu X,Han P,Cheng Y,Gao Y,Zhang R,Yang Y,Chen Z,Hu J,Chen Y,Xu M

更新日期：2016-01-01 00:00:00

abstract：:Conclusion Neck dissection after radiotherapy increased the risk of aspiration as a late effect in a sub-sample of patients treated for head and neck cancer in the ARTSCAN study. Patients treated with accelerated fractionation (AF) developed aspiration, with or without coughing, more frequently than patients treated w...

journal_title：Acta oto-laryngologica

authors： Lindblom U,Nilsson P,Gärskog O,Kjellen E,Laurell G,Wahlberg P,Zackrisson B,Levring Jäghagen E

更新日期：2016-01-01 00:00:00

abstract：CONCLUSION:Cochlear implantation (CI) for Japanese single-sided deafness patients resulted in improved speech perception, increased sound localization accuracy, and reduced tinnitus handicap. OBJECTIVES:This study reports results for five adult SSD cases with CI, focusing on the benefits they obtained in terms of spee...

journal_title：Acta oto-laryngologica

authors： Kitoh R,Moteki H,Nishio S,Shinden S,Kanzaki S,Iwasaki S,Ogawa K,Usami S

更新日期：2016-01-01 00:00:00

abstract：CONCLUSION:This study revealed that endolymphatic hydrops (EH) reduced in some cases with Ménière's disease (MD) treated conservatively. It appears that the EH reduction was associated with improvement of the clinical symptoms. OBJECTIVES:The relationship between the degree of EH and clinical symptoms is not clear at ...

journal_title：Acta oto-laryngologica

authors： Suga K,Kato M,Yoshida T,Nishio N,Nakada T,Sugiura S,Otake H,Kato K,Teranishi M,Sone M,Naganawa S,Nakashima T

更新日期：2015-09-01 00:00:00

abstract：CONCLUSIONS:Intra-arterial high-dose cisplatin chemoradiation (CRT-IA) with sodium thiosulfate (STS) causes relatively less severe cisplatin ototoxicity than intravenous cisplatin chemoradiation without STS (CRT-IV). The results of this study also suggest that early detection of ototoxicity is possible by testing the h...

journal_title：Acta oto-laryngologica

authors： Ishikawa E,Sugimoto H,Hatano M,Nakanishi Y,Tsuji A,Endo K,Kondo S,Wakisaka N,Murono S,Ito M,Yoshizaki T

更新日期：2015-09-01 00:00:00

abstract：CONCLUSION:Surgery remains the preferred option for large vestibular schwannoma (VS). The presence of unpredictable intraoperative difficulties may convince the operator to suspend the surgery to avoid risks to patient life. Additional surgeries may be mandatory and are better performed using a transcochlear approach. ...

journal_title：Acta oto-laryngologica

authors： Kunimoto Y,Lauda L,Falcioni M,Taibah A,Hasegawa K,Sanna M

更新日期：2015-09-01 00:00:00

abstract：CONCLUSION:The developed software (HITCal) may be a useful tool in the analysis and measurement of the saccadic video head impulse test (vHIT) responses and with the experience obtained during its use the authors suggest that HITCal is an excellent method for enhanced exploration of vHIT outputs. OBJECTIVE:To develop ...

journal_title：Acta oto-laryngologica

authors： Rey-Martinez J,Batuecas-Caletrio A,Matiño E,Perez Fernandez N

更新日期：2015-09-01 00:00:00

abstract：CONCLUSION:The results support that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system. OBJECTIVES:Numerous researches have been done about the risks of exposure to the electromagnetic fields that occur during the use of these devices, especially the effe...

journal_title：Acta oto-laryngologica

authors： Özgür A,Tümkaya L,Terzi S,Kalkan Y,Erdivanlı ÖÇ,Dursun E

更新日期：2015-08-01 00:00:00

abstract：CONCLUSION:Lactobacillus rhamnosus GG (L.GG) was present in all adenoids of children receiving the L. GG product. However, since L.GG was also found from the placebo group, one cannot confirm its effect on the occurrence of rhinovirus (RV) or enterovirus (EV). OBJECTIVES:The present study was conducted to determine wh...

journal_title：Acta oto-laryngologica

authors： Swanljung E,Tapiovaara L,Lehtoranta L,Mäkivuokko H,Roivainen M,Korpela R,Pitkäranta A

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:This study adopted an inner ear test battery to investigate the causes of acute sensorineural hearing loss in patients with hematological disorders. METHODS:During the past 20 years, the authors have experienced 14 patients with hematological disorders, i.e. leukemia or aplastic anemia, having acute sensorin...

journal_title：Acta oto-laryngologica

authors： Lin CT,Chiang CW,Young YH

更新日期：2015-07-01 00:00:00

abstract：CONCLUSION:This study provides evidence that histamine induced MUC5AC mRNA expression through the activation of the core region of its promoter. It may also help in approaching new therapeutic strategies in airway mucins hypersecretory diseases. OBJECTIVE:Mucin hypersecretion characterizes several respiratory diseases...

journal_title：Acta oto-laryngologica

authors： Xu F,Zhang L,Gao J,Wang D

更新日期：2015-07-01 00:00:00

abstract：CONCLUSION:We demonstrated an early increase in aquaporin 2 (AQP2) expression in a motor nerve (extratemporal facial nerve, FN) following acute peripheral compression (crush), concomitant to effective development of motor dysfunction (facial palsy). The early increase in AQP2 expression that occurred concomitantly with...

journal_title：Acta oto-laryngologica

authors： Neiva FC,Borin A,Lee KS,Dias MV,Rodrigues BR,Testa JR,Cruz OL,Covolan L

更新日期：2015-07-01 00:00:00

abstract：CONCLUSION:Gene transcription and protein expression of α-ENaC showed a divergent expression in association with the development of OME induced by barotrauma. OBJECTIVES:ENaC was identified to mediate the fluid absorption through epithelia of the middle ear. This study was designed to investigate the involvement of EN...

journal_title：Acta oto-laryngologica

authors： Xu J,Zong Y,Li X,Zhang Y,Li J

更新日期：2015-07-01 00:00:00

abstract：:Laryngoscopy in cases of sulcus vocalis reveals bowed vocal folds, resulting in a spindle-shaped chink with glottal incompetence. The anatomic and functional problems and resulting incomplete glottal closure during phonation lead to the presenting symptoms of breathy hoarseness, decrease in maximum phonation time (MPT...

journal_title：Acta oto-laryngologica

authors： Tsunoda K,Fujimaki Y,Nito T,Yamasoba T,Tayama N,Makiyama K,Murofushi T,Tsunoda A,Ohshima K,Nishiyama K,Kano S,Niimi S

更新日期：2015-06-01 00:00:00

abstract：CONCLUSION:Compared with normal-weight individuals, obese young adults exhibited a significantly higher taste threshold for salty taste. Smoking also affected taste functions in this population. OBJECTIVE:The aim of this study was to investigate the differences in taste detection thresholds between normal-weight and o...

journal_title：Acta oto-laryngologica

authors： Park DC,Yeo JH,Ryu IY,Kim SH,Jung J,Yeo SG

更新日期：2015-05-01 00:00:00

abstract：CONCLUSIONS:This is the first report of mandibular reconstruction using the retroauricular (RA) or the modified face-lift (MFL) approach in head and neck cancer. This approach may have advantages over the conventional approach, especially in its superior aesthetic results. OBJECTIVE:The fibular osseous or osteocutaneo...

journal_title：Acta oto-laryngologica

authors： Kim WS,Jittreetat T,Nam W,Sannikorn P,Choi EC,Koh YW

更新日期：2015-05-01 00:00:00

abstract：CONCLUSION:The outcomes of extended subtotal facial nerve decompression via the transmastoid approach were good for facial palsy after temporal bone fracture (TBF). Surgical decompression should be carried out as soon as possible within 8 weeks after trauma. OBJECTIVE:To present outcomes of facial palsy after TBF via ...

journal_title：Acta oto-laryngologica

authors： Liu Y,Liu S,Li J,Chen X,Sun J,Li Y

更新日期：2015-03-01 00:00:00

abstract：CONCLUSION:Bilateral electric acoustic stimulation (EAS) effectively improved speech perception in noise and sound localization in patients with high-frequency hearing loss. OBJECTIVE:To evaluate bilateral EAS efficacy of sound localization detection and speech perception in noise in two cases of high-frequency hearin...

journal_title：Acta oto-laryngologica

authors： Moteki H,Kitoh R,Tsukada K,Iwasaki S,Nishio SY,Usami S

更新日期：2015-02-01 00:00:00

abstract：CONCLUSION:Delayed facial palsy after tympanoplasty had no predisposition for gender or side. It seemed that prednisolone alone without antiviral drugs was enough for the treatment of delayed facial palsy after tympanoplasty. OBJECTIVE:To analyze the clinical characteristics and prognosis of delayed facial palsy after...

journal_title：Acta oto-laryngologica

authors： Zhou Y,Song R,Li Y

更新日期：2015-02-01 00:00:00

abstract：CONCLUSION:This work demonstrated that juvenile nasopharyngeal angiofibromas (JNAs) express high levels of hormone receptors and vascular endothelial growth factor (VEGF) compared with normal nasal mucosa. The interaction between hormone receptors and VEGF may be involved in the initiation and growth of JNA. OBJECTIVE...

journal_title：Acta oto-laryngologica

authors： Liu Z,Wang J,Wang H,Wang D,Hu L,Liu Q,Sun X

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:On average, adult CI recipients report a moderate sound quality using the Dutch version of the HISQUI19 questionnaire. These results are correlated with their age, speech perception scores, CI aided hearing thresholds, and the SSQ5 and the APHAB questionnaire. BACKGROUND:The general aim of the study was to ...

journal_title：Acta oto-laryngologica

authors： Mertens G,Kleine Punte A,De Bodt M,Van de Heyning P

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:Patients with posterior semicircular canal dehiscence (PSCD) have low frequency conductive hearing loss similar to patients with superior semicircular canal dehiscence (SSCD) secondary to a pathologic third window. OBJECTIVES:PSCD can result in conductive hearing loss, but the magnitude of this hearing loss...

journal_title：Acta oto-laryngologica

authors： Bear ZW,McEvoy TP,Mikulec AA

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:The results show that the DUET2 offers users speech perception that is equivalent to or better than the DUET. Moreover, the DUET2 offers subjective benefits above those provided by the DUET. BACKGROUND:The DUET is a combination of hearing aid and CI in one device for electric acoustic stimulation. Since its...

journal_title：Acta oto-laryngologica

authors： Kleine Punte A,Mertens G,Cochet E,De Bodt M,Van de Heyning P

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:The addition of transoral robotic surgery (TORS) in the diagnostic management of patients classified with head and neck squamous cell carcinoma of unknown primary (SCCUP) is promising and appears to improve detection rates of the primary tumour. The approach presented in this first Scandinavian study could p...

journal_title：Acta oto-laryngologica

authors： Channir HI,Rubek N,Nielsen HU,Kiss K,Charabi BW,Lajer CB,von Buchwald C

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:Cone Beam Computed Tomography (CBCT) can be widely used in imaging of bony structures of the anterior and lateral skull base. Significant differences of applied dosages result from the different protocols of the various indications. OBJECTIVES:CBCT is increasingly being used in head and neck imaging. Until ...

journal_title：Acta oto-laryngologica

authors： Stutzki M,Jahns E,Mandapathil MM,Diogo I,Werner JA,Güldner C

更新日期：2015-01-01 00:00:00